Science • Spermidine LIFE
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Cell Research - Our Passion.

It is widely known that cells play a diverse role in our metabolism. However, the importance of various cell functions and their effects on our health have by no means been fully researched. Therefore, research continues to be carried out worldwide and new discoveries are made regularly. The topics of cell renewal and cell aging are a major focus of scientific research.

Scientific research is our passion: In cooperation with the University of Graz, we are also continuously researching cells and spermidine.


Cells. The smallest unit of life.

The role of the cell in the body.

Everywhere in our body there are cells, the functionality of which is essential for our general state of health. They are the smallest unit of life, but they play a major role in the human body, because a multitude of essential processes take place in them.

They store certain substances, such as oxygen, and release them when necessary. They also carry out their own metabolic processes to produce energy. The small power plants of our cells, the mitochondria, utilize the energy obtained from food through blood and make it available to our body when needed. In addition, they can divide, communicate with each other and send vital signals to other cells and organs.


Different cell type - different task.

There are various types of cells in our body, which age at different speeds and have different life spans. Cell production and cell purification slows down and a naturally induced cell loss occurs with increasing age. The functions of the cells begin to slow down and often stop working as they should. To a certain extent, this is completely normal. However, if an above-average number of cells die or become obsolete, our organism becomes ill.

Keeping cells active.

If we want to stay in good health for a long time, we must take care of our cells. Regular exercise, a nutritious, varied diet, sufficient sleep and avoiding stress helps us keep our cells in good shape. The active maintenance of the body’s own cell recycling and cell renewal process called autophagy, is especially important. It ensures that harmful cellular waste is disposed of to keep our cells young and healthy. Although, this process decreases with age, it can be supported by a healthy lifestyle, a conscious diet and regular, long breaks between meals.


Cells have different life spans: some cells of the stomach only live for two days, skin cells renew themselves every three to four weeks. Red blood cells live for about three months, while bone cells are active for as long as 25 years.

Cell care.

Avoiding oxidative stress is also of great importance in cell care. Disturbing the balance between antioxidants and free radicals can lead to a cellular stress state which can damage cell structures. Free radicals are not exclusively harmful. They activate our cell power plants and support our immune system by suppressing degenerated cells and pathogens. Nevertheless, the free radicals used by the body must be compensated. If this does not happen, the harmful effect of the free radicals outweighs the harmful effects and cell and organ damage can occur. Possible causes for this are an unbalanced diet, stress, medication, drugs, environmental toxins, excessive physical exertion and UV radiation. By avoiding these possible triggers and ensuring a balanced diet, oxidative stress can be prevented. The intake of antioxidants (such as zinc) through food and the sufficient supply of certain vitamins (e.g. vitamin B1) additionally protect the cells from oxidative stress*.


A highly discussed subject.

The endogenous substance spermidine is a so-called polyamine, which is found in every cell of the human body. Spermidine is a natural component of our cells that is produced by our organism.

Although our body is able to produce spermidine itself, its own production of spermidine decreases considerably with age. As a result, the body has less at its disposal.

Nonetheless, spermidine is not only produced by the body, but can also be found in a wide variety of fruits, vegetables, meat and cheese. We produce around a third of the spermidine content ourselves. The rest can be ingested through food and supplements.

Scientific Advisory Board

An international team of experts.

We challenge some of the best scientists and cell researchers with our vision and are accompanied by a renowned, international advisory board whose task is to critically review our work and support us with ideas and expertise.

With sustainable research and development of substances that optimize life, we have a common goal.

Our advisory board members support us in driving innovation forward with their experience from various fields of medicine and research.

Lorenzo Galluzzi, Ph.D.
Most cited young researcher
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Guido Kroemer, Ph.D.
Most cited autophagy researcher
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Frank Madeo, Ph.D.
Discovered the Spermidine effect
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Rainer Oberbauer, Ph.D.
Nephrology & Dialysis
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Thomas Pieber, MD, Ph.D.
Internal medicine & endocrinology
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Stephan Sigrist, Ph.D.
Neurobiology & genetics
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Peter Valent, MD, Ph.D.
Haematology & haemostaseology
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Elizabeth Yurth, MD
Med. Director Longevity Institute
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Spermidine and the University of Graz.

Due to the revolutionary research at the University of Graz, Austria, spermidine has gained worldwide attention in recent years.

Currently, around 100 international research teams are investigating the substance spermidine. Despite the short investigation period for scientific reasons, there are few substances that are more intensively researched than spermidine.